The Division of Medicinal Chemistry

Spring 1998 Newsletter

Annette M. Doherty - Secretary

Candidates for Election

A Nominating Committee composed of three members of the Division was formed to identify a list of candidates for election. In accordance with Division Bylaws the membership of this committee remains anonymous. Their selection of candidates is as follows:

Jane V. Aldrich (Vice-Chair)
Laurence H. Hurley (Vice-Chair)
One to be elected

Donald E. Bergstrom (Academic Councilor)
Gary L. Grunewald (Academic Councilor)
One to be elected

The deadline for the ballot to cast your vote will be no later than July 15, 1998. National and Divisional Affiliates may not vote. Ballots will be sent to all members shortly.

The other officers of the Division for 1998, as previously elected are listed below:

Kenneth Kirk, Chair
Amy Trainor, Vice-Chair
Annette M. Doherty, Secretary
Leslie G. Humber, Treasurer
Dale L. Boger, Councilor
James McCarthy, Councilor
Michael F. Rafferty, Councilor
Leroy B. Townsend, Councilor
Thomas J. Perun, Past Chair

216th American Chemical Society Meeting, Boston, MA, August 23-27, 1998.

The preliminary program for the Medicinal Chemistry Division is outlined below. In addition to the listed symposia the presentations by student fellowship winners will be on the program. There will also be several general oral and poster sessions and the final program will be available in an upcoming issue of C and E News, as well as the Division Homepage on the World Wide Web.

Boston, Fall 1998 Program
Symposium Title (Organizer/Chair)

Sun AM - General oral papers (A. Doherty)
Sun PM - General oral papers (A. Doherty)
Sun PM - MS in Drug Discovery Research (S.Hays/J. Loo)
Sun EVE - Poster Session (A. Doherty)
Mon AM - Urogenital Diseases (K. Cooper/TBA)
Mon PM - Combinatorial Biosynthesis (K. Janda, K. Shiosaki/TBA)
Tues AM - Awards/Fellowships/ General Oral (A. Doherty)
Tues PM - Pain (S. Hays/D. Wustrow)
Wed AM - Malaria Therapies (J. Ellman)
Wed PM - Viral Hepatitis (K. Shiosaki)
Wed All - Co-Running Poster Session (A. Doherty)
Thurs AM - Retinoids and Cancer (W. Brouillette, D.D. Muccio)
Thurs PM - New Targets for Treatment of Vascular Disease/Diabetes PPARS (D. Flynn/T. Willson)

The Annual Division Business Meeting scheduled to take place after the Division of Medicinal Chemistry's Executive Committee meeting is open to all members. Members are encouraged to attend. The meeting will take place at the location of the poster session 7.00-7.30pm on Sunday August 23rd, 1998.

217th American Chemical Society Meeting, Anaheim, CA, March 21-25, 1999.

You are invited to submit an abstract for the Anaheim ACS Meeting, March 21-25, 1999. The deadline for abstracts is December 1, 1998. The short (150 word) abstract, typed on the standard ACS form should be mailed to the Secretary at the address on p.1 in this Newsletter. Abstract forms may be obtained from the ACS office by calling the Membership Service Center 1-800-451-9190. If more convenient, we will also accept original copy on the form from the World Wide Web. Faxed abstracts are not acceptable. A 1,000 word expanded abstract or equivalent supporting documentation is required for oral presentations. This additional information will be used to help select the oral papers from the many requests.

The following symposia are being organized:

Anaheim, Spring 1999 Program
Symposium Title (Organizer/Chair)

Sun AM General Oral Papers (A. Doherty)
PM General Oral Papers (A. Doherty)
Eve POSTERS (A. Doherty)
Mon AM Pharmacogenomics/Med. Chem. Applications (J. Schwab)
PM Pharmacogenomics/Med. Chem. Applications (J. Schwab)
Co-run PM Endothelins (P. Woster)
Tues AM PDE Inhibitors (I - VIII) (K. Cooper/R. Wrigglesworth)
PM Adrenergics (S. Hays/D. Miller)
AM/PM Co-run POSTERS (A. Doherty)
Wed AM Screening and Profiling (K. Shiosaki/R. Wexler)
PM Screening and Profiling (K. Shiosaki/R. Wexler)
Co-run PM Antivirals (S. Hays/V. Prasad)
Thurs AM Small Molecule Ligands: Targets in Protein/ Protein Interactions (J. Ellman)
PM Use of Natural Products to Exploit New Discovery Targets: FK 506 (K. Wright)

Suggestions for symposia at future meetings are invited from the Division members. Well thought-out proposals with possible speakers and topics should be sent to the Division Secretary for discussion at the Divisional Long Range Planning Committee meetings held twice a year at the National meetings.

National Medicinal Chemistry Symposium

The 1998 National Medicinal Chemistry Symposium will be held at the Virginia Commonwealth University in Richmond on June 13-18, 1998. Professor Donald Abraham will be the General Chair and Dr. Thomas Perun will be the Program Chair.

Dr. John Topliss is the 1998 recipient of the Division of Medicinal Chemistry award sponsored by the Medicinal Chemistry Division of the ACS. The award address will be given on Sunday evening. Topics at this meeting include:

Drug Metabolism in Drug Design
Structure-Based Drug Design
Prodrugs and Drugs Targeting
Carbohydrate Mimetics
Chemokines
p53 as a Drug Target
Molecular Modeling in the 21stt Century

The year 2000 National Medicinal Symposium will be held in Kansas and chaired by Professor Gary Grunewald.

Other Meetings of Interest

Residential School on Medicinal Chemistry, June 8-12, 1998, Madison, New Jersey. Contact Professor William J. Houlihan, C.A. Dana Research Institute, Drew University, Hall of Sciences, Rm 331, Madison, New Jersey, 07940, USA. Tel: 973-408-3633, Fax: 973-408-3504, e-mail: resmed@drew.edu. The complete program and registration form can be found on the school web site at http://daniel.drew.edu/~resmed.

XIVth International Conference on Phosphorus Chemistry, July 12-17, 1998, Cincinatti, Ohio. Contact Dr. Frank H. Ebetino, Procter and Gamble Pharmaceuticals, Health Care Research Center, P.O. Box 8006, Mason, OH 45040-8005, phone: 513/622-3630, fax: 513/622-1195, e-mail: ebetino.fh@pg.com. Program and registration information can be found at http://www.usc.edu/dept/chemistry/ICPC14/index.html.

XVth International Symposium on Medicinal Chemistry, September 6-10, 1998, Edinburgh, Scotland. Contact Dr. John Gibson, RSC Tel: 44-171-437-8656, Fax: 44-171-734-1227, E-Mail: conferences@rsc.org

1998 ACS Regional Meeting Dates

June 1 - 3, 1998 31st Great Lakes Regional Mtg. General Chair: Alex Hill, U of Wisconsin, Chemistry Dept., Milwaukee, Wis. 53201, (414) 229-4256, fax (414) 229-5530, e-mail: alex@csd.uwm.edu

June 17 - 20, 1998 53rd ACS Northwest Regional Meeting; Columbia Basin College, Pasco, Wash. General Chair: Karen Grant, Columbia Basin C, Math/Science Div., 2600 North 20th Ave., Pasco, Wash. 99301, (509) 547-0511, e-mail: kgrant@ctc.edu

November 1 - 3, 1998 54th Southwest Regional Meeting, Baton Rouge, La. General Chair: Carl Hudson, Exxon R&D Labs, P.O. Box 2226, Baton Rouge, La. 70821, (504) 359-4890, fax (504) 359-7325.

November 4 - 7, 1998 33rd ACS Midwest Regional Meeting; Broadview Hotel, Wichita, Kan. General Co-Chairs: Charles Greenlief, Emporia State U, Dept. of Chemistry, CB 4030, Emporia, Kan. 66801-5087, (316) 341-5990, fax (316) 341-6055, e-mail: greenlic@esumail.emporia.edu

Phillip Wahlbeck, Dept. of Chemistry, Wichita State U, Wichita, Kan. 67260-0051, (316) 689-3120, fax (316) 689-3431, e-mail: pgwahlbe@twsuvm.uc.twsu.edu

November 4 - 7, 1998 50th ACS Southeast Regional Meeting; Sheraton Imperial, Research Triangle Park, N.C. General Chair: Bill Switzer, North Carolina State U, Chemistry Dept., Box 8204, Raleigh, NC 27695-8204, (919) 775-0800 ext. 944, fax (919) 515-5079, e-mail: switzer@chemdept.chem.ncsu.edu

Schedule of Major Meetings of the American Chemical Society

216th Fall 1998 August 23-27 Boston, MA
217th Spring 1999 March 21-25 Anaheim, CA
218th Fall 1999 August 22-27 New Orleans, LA
219th Spring 2000 March 26-31 Las Vegas, NV
220th Fall 2000 August 20-25 Washington, D.C.
221st Spring 2001 April 1-6 San Francisco, CA

1998 Division of Medicinal Chemistry

Predoctoral FellowshipAawards

Five $20,000 fellowships have been awarded to students in graduate programs engaged in medicinal chemistry research. A number of applications were reviewed by a committee of experts from both Academia and Industry. The sponsoring companies are: Abbott, Bristol-Myers Squibb, Hoechst-Marion Roussel, Wyeth-Ayerst, Parke-Davis. The recipients and mentors are:

Lara Mahal (Carolyn Bertozzi) University of California/Berkley
Chris Boyce (Dale Boger) Scripps Research Institute
Amy Dounay (Craig Forsyth) University of Minnesota
Craig Masse (James Panek) Boston University
Betsy Jamieson (Stephen Lippard) M.I.T.

Congratulations to the winners of these awards ! We also thank the other applicants for the excellent proposals which were submitted.

1999-2000 Predoctoral Fellowships

The ACS Division of Medicinal Chemistry announces the continuation of its Fellowship program. Five $20,000 fellowships will be awarded in 1999, through the sponsorship of the following companies: Abbott Laboratories, Bristol-Myers Squibb, Hoechst-Marion Roussel, Parke-Davis Pharmaceutical Research, and Wyeth-Ayerst Research. The awards are for predoctoral students engaged in medicinal chemistry research in a Medicinal Chemistry, Pharmaceutical Chemistry, Biochemistry, or Chemistry department listed in the current ACS Directory of Graduate Research.

Nominations should include a complete student curriculum vitae, including education and work experience; a student bibliography, including reprints of articles; a complete project description including rationale (five-page limit) prepared by the candidate; transcripts of all post-high school work, including Graduate Record Examination scores (if available); three letters, including a nomination letter from the student's research advisor; and a letter from a university official with a commitment to cover tuition and all fees granted to other regular graduate students.

Applicants must be U.S. citizens or permanent resident visa holders at the time of application and must have at least one year of graduate school remaining at the time an award would begin September 1, 1998. Additional information (including a complete set of guidelines) can be obtained from Dr. Kenneth Kirk, Ph.D., Laboratory of Bioorganic Chemistry, NIDDK, NIH, Building 8A, Room B1A-02, Bethesda, MD 20892, Phone (301) 496-2619, Fax (301) 402-4182, e-mail : kennethk@bdg8.niddk.nih.gov All application materials for the awards are due on January 15, 1999 and must be received by Dr. Kenneth Kirk (1999 Past-Chair) at the above address.

Dues - Medicinal Chemistry Division

There will be an increase in dues for regular division members by $2 from $17 to $19. The reasons for the increase are:

Increased publication costs for our yearly book "Annual Reports in Medicinal Chemistry".
Publication of a division membership directory to be provided to all members. The last division directory was published in 1994 and requires updating.

The last division dues increase was in 1992 and we have tried to ensure that this increase (1999) will be as small as possible to offset our increased outgoing costs while providing the above services to our members. Dues for student members of the Division will not increase.

Changes to Bylaws

The council of the American Chemical Society approved amendments to the Constitution and Bylaws to change all documents to reflect gender neutrality. In addition specifications to election as a division officer have been clarified to reflect that it is not possible to be nominated for re-election.

Nominations for the 1999 Smissman Bristol-Myers Squibb Award

Nominations are being solicited for the 1999 Smissman Bristol-Myers Squibb Award. This award is open to any scientists who, through his/her work or teaching, has had an impact on the way in which medicinal chemistry is practiced. The emphasis shall be placed on the long-term contributions, rather than a single important discovery.

Previous recipients of the award include Corwin Hansch (1975), Alfred Burger (1977), Everette May (1979), Adrien Albert (1981), Hamao Umezawa (1983), G. Ariens (1985), Robert Abeles (1987), Lester Mitscher (1989), Philip Portoghese (1991), Leroy Townsend (1993), John Montgomery (1995), and Joseph Cannon (1997).

Nomination documentation, including a letter of nomination, a seconding letter, and a recent CV of the nominee, should be sent to Prof. David E. Nichols, Dept. of Medicinal Chemistry and Molecular Pharmacology, School of Pharmacy, Purdue University, W. Lafayette, IN 47907 by September 1, 1998. Nominators are encouraged to contact Professor Nichols prior to submission at: (765)-494-1461 (phone), (765)-494-1414 (fax), or drdave@pharmacy.purdue.edu.

Availability of R15 Area Grants

R15 area grants are available to institutions that have granted baccalaureate degrees to 25 or more individuals who have obtained academic or professional doctoral degrees in the health related sciences during the period 1986-1995. There is more information available at the following website address:

http://www.nih.gov/grants/guide/pa-files/pa-97-052.htlm

Electronic Communication Committee

Since the last National Meeting of the American Chemical Society, the Computer Committee has made continued efforts to improve Division online services. Our activities in specific areas are outlined below:

The Division E-Mail Directory. The Division E-Mail directory is now a 127 kB text file that is approximately 102 pages long (single column), and contains approximately 650 entries. This represents 9.2% of the Division membership. The size of the file now dictates that it is only available through the World Wide Web page, where it is only available in HTML format. The list may be displayed through the Web, and is searchable by letter. There is no longer a text version of the file available for download. There is now a password script on the directory which allows password security for the list of Divisional E-mail addresses. This script is now being "beta tested".

The Division LISTSERV, ACSMEDI. The LISTSERV has now grown to include 630 members (8% of the Division membership). The address for posting messages continues to be:

acsmedi@lists.wayne.edu

while the address for commands remains:

listserv@lists.wayne.edu

The ACS Medchem Division WWW Homepage. The World Wide Web page for the Division continues to expand, and is available at any time at the following address:

http://wiz2.pharm.wayne.edu

The address for the page has been made available to the membership through the LISTSERV, is sent automatically to anyone signing up for the E-Mail list, and is also published in each Division newsletter. Our page is indexed under all of the search engines provided through the Net Search option of Netscape, and is thus available to Internet users around the world through a keyword search. ACS has included our address in all of its publications pertaining to Internet services, and has linked to our page from the Divisions section of the ACS homepage. We are hyperlinked to the Organic Division page, as well as to a variety of sites of interest to chemists. A large number of new hyperlinks have been added, allowing users to link to a number of services, organizations and on-line journals. Pertinent links are continually added. There is now a section dedicated to academic MedChem sites, and a similar section devoted to industry MedChem sites has been established.

Candidates for Vice-Chairman

Jane V. Aldrich

Dr. Jane Aldrich received her Ph.D. in medicinal chemistry from the University of Michigan in 1983 under the direction of Dr. Raymond Counsell. She began her research on the design and synthesis of opioid peptide analogues as an NIH postdoctoral fellow with Dr. Philip Portoghese at the University of Minnesota. She joined the faculty of the College of Pharmacy at Oregon State University in 1987 as an Assistant Professor of Medicinal Chemistry and was promoted to Associate Professor in 1993. In 1995 she moved to her current position of Associate Professor in the Department of Pharmaceutical Sciences in the School of Pharmacy at the University of Maryland, Baltimore.

Dr. Aldrich's research involves the design and synthesis of peptide and peptidomimetic analogues, primarily focusing on opioid peptide analogues, including affinity labels, as probes of opioid receptors. In addition, she is involved in the design and synthesis of peptides and peptidomimetics with potential antitumor activity. This research includes examination of synthetic methodology (both solution and solid phase approaches), as well as exploration of structure-activity relationships. Her recent publications include a chapter on analgesics in the recent edition of Burger's Medicinal Chemistry and Drug Discovery.

Dr. Aldrich has been active in the Medicinal Chemistry Division of the ACS as well as other professional activities. She has served on the Division's Long Range Planning Committee (1995-1997) and on the Fellowship Committee (1996-1998). She has organized and chaired two symposia for the Division, on "Cysteine Proteases" at the national ACS meeting in Las Vegas in 1997 and on "Prodrugs and Drug Targeting" for the upcoming 26th Medicinal Chemistry Symposium in Richmond this summer. She also co-chaired a session on "Combinatorial Approaches in Biology" at the NIH Symposium on Bioengineering in February. Other professional activities include editor of the journal Letters in Peptide Science, editorial board member for the Journal of Peptide Research, and chair of the Student Affairs Committee of the American Peptide Society. She has also served on several special review committees for NIH and the Army, and has been a grant reviewer for the Petroleum Research Fund, NSF and the Medical Research Council of Canada.

Jane V. Aldrich, Ph.D.
Associate Professor
Dept. of Pharmaceutical Sciences
School of Pharmacy
20 North Pine Street, Room 503
University of Maryland
Baltimore, MD 21201-1180
Voice: (410) 706-6863
Fax: (410) 706-0346
E-mail: jaldrich@pharmacy.ab.umd.edu

Laurence H. Hurley

Laurence H. Hurley, George H. Hitchings Regents Chair in Drug Design and Head of the Laboratory for Drug Design, Drug Dynamics Institute, College of Pharmacy, The University of Texas at Austin, was born in 1944 in Birmingham, England. He received his B.Pharm. (Honors) in 1967 from Bath University (U.K.) and his Ph.D. (Medicinal Chemistry) in 1970 from Purdue University. In 1972 he was appointed Assistant Professor at the University of Maryland School of Pharmacy; in 1973 he moved to the University of Kentucky as Assistant Professor; in 1977 he became Associate Professor; and in 1979, Professor. He joined the Drug Dynamics Institute in the College of Pharmacy at The University of Texas at Austin in 1981 and was appointed Professor of Medicinal Chemistry. Since September 1985, Dr. Hurley has served on the graduate faculties of the Department of Chemistry and Biochemistry and the Molecular Biology Program at The University of Texas. In 1995 he was appointed Director of Chemistry at the Institute for Drug Development, Cancer Therapy Research Center, San Antonio, Texas. He is founder and scientific director of Cyternex.

Dr. Hurley's present research interests are in the areas of design and development of antitumor and antibiotic agents. Over the last fifteen years, work from his laboratory has led to elucidation of the structures of the drug-receptor complexes for six different groups of compounds that are potentially useful in the treatment of cancer or bacterial infections. In cooperation with the pharmaceutical industry, several drugs developed with the aid of these studies have been evaluated in phase I and II clinical trials.

Dr. Hurley has served as principal investigator on over forty research grants, including awards from the National Institutes of Health, National Science Foundation, Research Corporation, The Welch Foundation, and a number of pharmaceutical companies. In 1989 and 1994 he was awarded Outstanding Investigator Grants from the National Cancer Institute. Dr. Hurley is a Fellow of the American Association for the Advancement of Science. He has been a consultant to a number of pharmaceutical companies and is currently senior editor for Journal of Medicinal Chemistry. He has been a member of the Long-Range Planning Committee and an alternate councilor of the Medicinal Chemistry Division of the American Chemical Society. Dr. Hurley was program and local arrangement chair for the 1990 ACS Medicinal Chemistry Symposium. Dr. Hurley has served as a grant reviewer for the National Institutes of Health (Member and Chairman, Bioorganic and Natural Products Study Section, 1984-1988), the National Science Foundation, and a number of private donor research award committees. He is a recipient of the 1988 George Hitchings Award in Innovative Methods in Drug Design, the 1989 Volwiler Research Achievement Award from the American Association of College of Pharmacy. He is the recipient of the 1992 APhA Research Achievement Award in Medicinal Chemistry and the 1994 ACS Medicinal Chemistry Award. In 1996 he was awarded a D.Sc. degree from Bath University.

Laurence H. Hurley, Ph.D.
George Hitchings Regents Chair in Drug Design
Drug Dynamics Institute, PHR 3.206
The University of Texas at Austin
Austin, Texas 78712-1074
Telephone: 512 471-4842
Fax: 512 471-2746
E-mail: dg-dna@mail.utexas.edu

Candidates for Councilor

Donald E. Bergstrom

Donald E. Bergstrom is Walther Professor of Medicinal Chemistry in the Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, Indiana.

Dr. Bergstrom has published extensively in the area of modified nucleoside synthesis and nucleic acid chemistry, and holds patents in the area of modified nucleobase synthesis and applications. Recent accomplishments include the development of a series of unusual nucleobase analogs with degenerate base pairing properties and the development of high precision sequence-specific synthetic nucleases.

Professor Bergstrom has served as a member of numerous ad hoc review committees at the National Institutes of Health in the Division of Research Grants, National Institute of General Medicine, and National Institute of Allergy and Infectious Diseases, and the U.S. Army Medical Research and Material Command. He was member of the Bioorganic and Natural Product Study Section, National Institutes of Health, 1988-1989, and a member of the AIDS and Related Research Study Section (ARRD), National Institutes of Health, 1990-93. Dr. Bergstrom is a consultant for Motorola Corp., Molecular Tool, Inc. and serves on the scientific advisory boards for Oridigm Corporation and Gemini Gene Therapy Inc. He is a member of the editorial boards of the journals Nucleosides and Nucleotides and Bioconjugate Chemistry. Professor Bergstrom was Chairman of the Red River Valley Section of the American Chemical Society in 1983 and Corresponding Secretary in 1982.

Professor Bergstrom received his B. S. degree in Chemistry from the University of Washington in June 1965, and his Ph.D. degree from the University of California, Berkeley in 1970. His thesis research at Berkeley, under the direction of Professor Henry Rapoport, was in the area of porphyrin synthesis. He began research in the area of nucleic acid chemistry as a postdoctoral research associate with Professor Nelson J. Leonard at the University of Illinois from 1970 until 1972.

Don Bergstrom
Department of Medicinal Chemistry & Molecular Pharmacology
Purdue University
West Lafayette, Indiana 47907
Telephone: (765)494-6275
Fax: (765)494-9193
e-mail: bergstrom@pharmacy.purdue.edu

Gary L. Grunewald

Gary L. Grunewald is Professor and Chair of the Department of Medicinal Chemistry at the University of Kansas. He was born in Spokane, Washington and earned B.S. degrees in chemistry and in pharmacy in 1960 from Washington State University. He attended graduate school at the University of Wisconsin in Madison as a Wisconsin Alumni Research Foundation Fellow and obtained the Ph.D. in organic chemistry in 1965. He accepted a faculty position in the Department of Medicinal Chemistry at Kansas and has been there ever since.

His research interests include mechanistic neurochemistry and drug design. He is a Victoria Professor in the InterSearch program (a joint training program between the University of Kansas and the Victorian College of Pharmacy of Monash University in Melbourne, Australia). He serves on the editorial boards of Bioorganic & Medicinal Chemistry and of Bioorganic & Medicinal Chemistry Letters, and has served as the editor of the Medicinal Research Series of Monographs (Marcel Dekker). He has served as chair of the Sybyl software user's group and received the Tripos Award in 1995 as Sybyl user-of-the-year. He was elected Chair of the Pharmaceutical Sciences section of AAAS in 1993 and was elected as a Fellow of AAAS in 1992. He is a member of the Board of Directors of the Medicinal & Bioorganic Chemistry Foundation and serves on the program committee for the Winter Conference on Medicinal & Bioorganic Chemistry held every two years in Steamboat Springs, Colorado.

Within the ACS Division of Medicinal Chemistry he has been chair of the Smissman Bristol-Myers Squibb Award nominating committee, served a 3-year term on the Long Range Planning Committee, and was elected Vice-Chair (1993) and served as Chair (1994) of the Division. He will be chair of the organizing committee for the Medicinal Chemistry Symposium to be hosted by the University of Kansas in 2000.

Gary L. Grunewald
Department of Medicinal Chemistry
The Universty of Kansas
Lawrence KS 66045-2506 USA
Voice: (785) 864-4497
Fax: (785) 864-5326
E-Mail: GGrunewald@ukans.edu

http://www.urc.ukans.edu/acadbroch/gradbroch/medchem/medchem.html
http://www.ukans.edu/home/ggrunewald

DIVISION OF MEDICINAL CHEMISTRY

ELECTION BALLOT

Click HERE to print out an official Division Election Ballot.

TRAVEL GRANTS

Division of Medicinal Chemistry

AMERICAN CHEMICAL SOCIETY

The Division of Medicinal Chemistry makes available 14 grants annually of $600 each to aid young chemists in presenting papers at the ACS National Meetings.

Eligibility: The applicant must be an ACS member (student or affiliate) and not have previously been the recipient of this award. Each university department can have only one awardee.

Criteria for Selection: In order of priority, the following criteria will be used for selection of awards: Graduate Student, Postdoctoral Fellow, Individual with less than five years post-Ph.D. experience. Scientific merit of paper to be presented will also be considered.

Application Procedure: Send applications to Annette Doherty, Parke-Davis Pharmaceutical Research, Division of Warner-Lambert Company, 2800 Plymouth Road, P.O. Box 1047, Ann Arbor, MI 48106-1047.

Awardees will be notified of the granting of such an award in sufficient time to that the awardee can pre-register for the meeting. The awards will be made at the Tuesday evening business meeting of the Division.

APPLICATION FORM TO BE SUBMITTED WITH ABSTRACT

1. Name of Applicant for Travel Grant ____________________________________.
2. Degree __________ Year Obtained:___________________
3. Present Institution:______________________________________
4. Department:________________________________________________________
5. Work to be reported was (check one or more):

a. Ph.D. Thesis ___________
b. M.S. Thesis ___________
c. Postdoctoral Fellowship ___________
d. Supported by:
1. Grant___________
2. Department ___________
3. Other__________________________________

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